Investor Presentaiton

H1'22 Highlights United States 'Santander US combines a strong depositary base in the Northeast with its nationwide auto finance, wealth management and corporate banking capabilities' ■ Strategic priorities ■■ Positioned to deliver above cost of capital returns across core businesses Refocus the US on our market leading consumer franchise Simplification: disciplined capital allocation. Discontinuing home lending operations and review certain C&I segments Synergies from 2021 strategic investments (Crédit Agricole / Amherst Pierpont / SC USA minority interests)² Branches 486 00 MA Employees 14,943 Total customers (mn) 4.7 Digital customers (mn) 1.0 • Customer loans (€ bn) 112 Customer funds (€ bn) 102 • Underlying attributable profit (€ mn) 1,090 ROTE¹ 21.3% Santander (1) Adjusted ROTE: adjusted based on Group's deployed capital calculated as contribution of RWAs at 12%. Using tangible equity, ROTE is 11.5%. (2) Acquisition of SC USA minority interest closed on 31 January 2022. Acquisition of Amherst Pierpont received regulatory approval in April 2022. Customer loans: Gross loans excluding reverse repos. Customer funds: customer deposits excluding repos + marketed mutual funds. More information at https://www.santander.com/en/about-us/where-we-are/santander-us 25

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