Investor Presentaiton

LOVVOLUS DURATION JEUVEAU EXTRA-STRENGTH PHASE II DURATION STUDY De KAPLAN-MEIER: RETURN TO BASELINE GLABELLAR LINES SCALE AT MAXIMUM FROWN Investigator assessment PERCENT OF PATIENTS (%) 100 80 60 40. 20 0 PRABOTULINUM ES 40U 183 (153, 211) DAYS, 26.1 WEEKS, 6.0 MONTHS PRABOTULINUM 20U 149 (130, 174) DAYS, 21.3 WEEKS, 4.9 MONTHS ONABOTULINUM 20U 148 (121, 174) DAYS, 21.1 WEEKS, 4.9 MONTHS 0 30 60 90 120 150 PRA 40U VS. PRA 20U: HR 1.892, P-VALUE 0.0109 PRA 40U VS. ONA 20U: HR 2.38, P-VALUE 0.0002 180 210 240 270 300 330 DAYS FROM TREATMENT 21

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