Q3 2020 Sales Performance slide image

Q3 2020 Sales Performance

Established vaccines and flu: durable assets provide portfolio backbone • Strategic lifecycle management enables a durable, cash generative portfolio Hepatitis franchise Supply agility created opportunities • Engerix-B approved in US in 1989 £874m in 2019 Havrix Hepatitis A Vaccine EngerixB recombinant hepatitis B vaccine • • DTP franchise 1 Hexa competition in Europe; expected in US Boostrix 65+ age expansion approved in US in 2011 gsk £1,317m in 2019 Pediarix BOOSTRIX Flu franchise • First approval in US in 2005 • Highly seasonal GSK: ~46m US doses in 2019/20 1. Diphtheria, tetanus, pertussis. 2. Porcine circovirus free formulation. £541m in 2019 Fluarix Quadrivalent Influenza Vaccine FluLaval Quadrivalent Influenza Virus Vaccine • Rotavirus Available in 115 markets 2 dose differentiation Pursuing PCV-free² liquid formulation for the US £558m in 2019 Rotarix 69 69
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