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Investor Presentaiton

Successful screening requires both adherence and performance 120M Avg Risk Individuals Ages 45 - 851 Adherence Colonoscopy FIT Cologuard 38% 2 43% 3 65%4 70M Screened Individuals 5 INVESTOR 20 DAY 23 50M Unscreened Individuals5 X GUARDANTâ„¢ 1. AACR Study, Cancer Prev Res (2020) 13 2. Singal AG, Gupta S, Skinner CS, et al. Effect of Colonoscopy Outreach vs Fecal Immunochemical Test Outreach on Colorectal Cancer Screening Completion: A Randomized Clinical Trial. JAMA. 2017;318(9):806-815. doi:10.1001/jama.2017.11389 3. Cancer Prevention Research. Impact of Patient Adherence to Stool-Based Colorectal Cancer Screening and Colonoscopy Following a Positive Test on Clinical Outcomes, https://aacrjournals.org/cancerprevention research/article/14/9/845/666815/Impact-of-Patient-Adherence-to-Stool-Based [aacrjournals.org.. ACS Colorectal Cancer Facts 2020-2022, 4. EXACT Sciences presentation at Goldman Sachs 44th Annual Global Healthcare Conference, June 2023 5. ACS Colorectal Cancer Facts 2020-2022 114
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