Investor Presentation Q1 2023

106 Investor presentation First three months of 2023 Insulin market size and volume share of growth and market share in International Operations Insulin market share and market size (DKK billion) Total Long- Acting 39% 51% Fast- acting 58% 16 Premix 80% 9 47% Human 8 28 20 Novo Nordisk Competitors Market growth A Market share 80% 60 -4.3% +0.8% Insulin volume: Market share Novo NordiskⓇ 10% 7% 60% -3.8% +2.4% 49% 4% 40% -0.1% -1.5% -0.6% 1% 20% -9.5% +2.3% 0% Feb -8.5% -0.8% 2020 -2% -2.4% -5% Feb 2023 -NN market share -Market growth (Right Axis) NN growth (Right Axis) Source: IQVIA, Feb 2023, LHS graph - Value, RHS Graph - Volume, MAT, all countries; Share of growth not depicted due to too high numbers; NN: Novo Nordisk

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