Investor Presentation - First Six Months of 2021

115 Investor presentation First six months of 2021 GLP-1 market share and market growth in North America Operations GLP-1 market growth and Novo Nordisk market share 60% 40% 20% GLP-1 market size and growth -25% 13 DKK billion 59% 17 51% 110 31% 25% 48.6% ~31% NAO 138 -1 50.8% 0% May 2018 NN market share NN share of growth May May 2020 2021 Market growth -NN growth Novo Nordisk Novo Nordisk Eli Lilly Others Competitors May 2021 Source: IQVIA, May 2021, value, MAT; NN: Novo Nordisk

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