Investor Presentation H1 2023

128 Investor presentation First six months of 2023 Insulin market size and volume share of growth and market share in Region China Region China Total Insulin market share and market size (DKK billion) Market growth A Market share Insulin volume: market share 80% 60% 52% 9 -38.9% +2.1% Long- acting 26% 3 Fast- acting 81% 1 Premix 88% 3 28% Human 2 Novo Nordisk Competitors 40% -48.2% -0.5% 0% -39.3% +0.3% -31.4% +7.0% -40% May 2020 -NN market share -29.4% -9.3% Source: IQVIA, May 2023, LHS graph - Value, RHS Graph - Volume, MAT; NN: Novo Nordisk; Region China covers Mainland China, Taiwan, and Hong Kong 43% 40% 20% 10% 0% -6% -31% -20% May 2023 NN share of growth Market growth (right axis) -NN growth (right axis)

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