Antofagasta Results Presentation Deck

2022 Guidance Cash costs and capital expenditure 1 2 $1.20/lb Net cash costs FY 2021 $1,777m 883 0.11 56 336 Copper By-product Input prices production production and price 503 +$0.35/lb 0.14 Guidance $1.7-1.9bn 0.10 2022E Cash costs $1.55/lb Net cash costs 2022E Growth Transport & corporate Sustaining (Mining) Mine development ● Net cash costs of $1.55/lb Increase primarily due to: o lower copper and by-products production at Los Pelambres and Centinela Capital expenditure² o higher input prices, particularly acid Includes CCP¹ target savings of at least $50 million Capital expenditure, is expected to be $1.7-1.9 billion Sustaining and mine development expenditure for the year increase to approximately $1.0 billion Development expenditure continues on the Los Pelambres Expansion project and at Centinela 2021 Cost and Competitiveness Programme Figures are based on cash flow and exclude Zaldívar. Attributable Zaldívar capital expenditure was $87m in 2021. Antofagasta plc | 2021 Preliminary financial results 18

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