Investor Presentaiton

Q2 2023 TALTZ SALES INCREASED 16% Millions U.S. sales increased 15% International sales increased 19% $704 $680 $606 $527 $488 Q1 Q2 Not for promotional use 2022 2023 $708 13 WK RA TRX SOM U.S. TRX SOM and Market Volume 7% 6% 5% 4% Lilly 230 Taltz 220 210 Market 200 190 3% 180 Q3 Q4 Jun 2021 Sep Dec Mar Jun Sep Dec Mar Jun 2021 2021 2022 2022 2022 2022 2023 2023 Source: IQVIA NPA TRX 3MMA, weekly data June 30, 2023; RA = rolling average TRx data is representative of the full molecule market 2023 Q2 EARNINGS 13 WK RA TRx Market Volume (000s) 32

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