INOVIQ Exosome Diagnostic Solutions

SubB2M technology platform Scientific rationale O Cancer cells have a distinct feature of adding different sugar Smolecules to the proteins they produce, which sets them apart ☐ from normal cells For personal use only Neu5Gc is a sugar molecule commonly found in cancer cells SubB2M is an engineered protein that preferentially binds to Neu5Gc SubB2M is a promising multicancer probe Incorporating SubB2M into existing cancer biomarker tests, may improve sensitivity and specificity for detecting various types of cancer Normal cells Expressing Neu5Ac glycoproteins 8 Neu5Gc = the sialic acid, N-glycolylneuraminic acid Changes in protein glycosylation Cellular transformation and progression Malignant cells Expressing Neu5Gc glycoproteins neu5Gc neu5Ac INOVIQ

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