Investor Presentaiton

Lack of screening compliance significantly impacts lives lost to colorectal cancer INVESTOR 20 DAY 23 GUARDANT™ 50K Colorectal cancer deaths per year 1,2 76% of CRC deaths are in individuals not up to date with screening³ 1. Bibbins-Domingo K, et al; JAMA. 2016;315(23):2564-2575. 2. US Preventive Services Task Force. Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2021;325(19):1965-1977. doi:10.1001/jama.2021.6238 3. Doubeni CA, et al. Gastroenterology. 2019;156(1):63-74.e6 102

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