Brepocitinib Overview & RVT-3101 Update

VTAMA Leads the Other Branded Topicals in Weekly TRX VTAMA Became the #1 Most Prescribed Branded Topical for Psoriasis 8 Weeks into Launch PsO Branded Topical Market - Weekly TRxs¹ 4,500 4,000 3,500 3,000 2,500 2,000 1,500 1,000 500 1/7 1/21 roivant 2/4 VTAMA (tapinarof) cream 1% ZZORYVE™ (roflumilast) cream 0.3% Source: IQVIA National Prescription Audit (NPA). 2/18 3/4 3/18 4/1 4/15 4/29 WYNZORA 5/13 5/27 6/10 ENSTILAR 6/24 7/8 ⚫DUOBRII 7/22 8/5 8/19 BRYHALI 9/2 9/16 ⚫LEXETTE 9/30 10/14 ⚫SORILUX 10/28 11/11 11/25 SOTYKTU 12/9 12/23 VTAMA AMA (tapinarof) cream 1% ENSTILAR ZZZ ZORYVE™ (roflumilast) cream 0.3% WYNZORA DUOBRII LEXETTE BRYHALI SORILUX SOTKYTU 16 For investor audiences only

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