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Immunology Investor Event

DupixentⓇ - Building a megabrand sanofi Indications Clinical program² Patients treated Demographics 2019 4 Positive pivotal trials in AD, Asthma and CRSwNP COPD and EoE initiated PN, CSU, BP planned 2022 61 7 new positive pivotal trials 12 new trials achieving FPI 7 new indications initiated >400K 125K adult, adolescent adult, adolescent, pediatric >4.9 million biologic eligible patients in AD U.S. and Ex-U.S.3 >2 million biologic eligible patients in Asthma and CRSWNP U.S. and Ex-U.S.4 Geographies 20 >50 Competition No other systemic biologic for Type 2 approved No other biologic with comparable breadth and scope of data on efficacy and safety across Type 2 indications and age groups 1. AD (18+Y, 12-17Y, 6-11Y), Asthma (12+Y, 6-11Y), CRSWNP; 2. For 2022, 7 positive pivotal trials (1 AD 6m-5Y, 1 Asthma 6-11Y, EoEx2, PNx2, 1 CSU), 12 FPI (1 AD 6m-5Y, 1 EoE ped, PNX2, CSUx2, 1 CIndU, 1 BP, 1 AFRS, 1 COPD, 1 CRSSNP, 1 CPUO), 7 New indications (CRSSNP, AFRS, CPUO, CIndU, BP, PN, CSU) 3. Japan, Germany, France, Italy, Spain, United Kingdom and China; 4. Japan, Germany, France, Italy, Spain & United Kingdom. 18 Immunology Investor Event
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