Investor Presentaiton

FDA-approved targeted therapy options are continuing to rapidly expand across solid. tumors (7) INVESTOR 20 DAY 23 (11) 89 (12) 78 71 (10) 59 (2) (11) (5) 47 49 (6) 36 (6) 31 (5) 25 (3) (2) (1) (3) 11 13 14 19 (New) Cumulative (1) (2) (1) 1 (1) 3458 2001 2003 2004 2005 2006 2007 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 GUARDANT™ Zhong et al. Signal Transduction and Targeted Therapy, 2021. 54 54

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