Retail Banking Performance Update

North America (Constant EUR mn) Change Change Q1'21 Q2'21 Q3'21 Q4'21 Q1'22 Q2'22 Q3'22 Q4'22 Q4'22/Q3'22 2021 2022 2022/2021 Net interest income 2,268 2,264 2,280 2,292 2,291 2,382 2,520 2,512 -0.3% 9,105 9,705 +6.6% Net fee income 519 468 430 436 478 500 493 487 -1.1% 1,853 1,958 +5.7% Gains (losses) on financial transactions and other 359 343 361 217 235 139 99 180 +82.9% 1,281 653 -49.0% Total revenue 3,146 3,075 3,071 2,946 3,003 3,021 3,112 3,180 +2.2% 12,238 12,316 +0.6% Operating expenses (1,317) (1,363) (1,424) (1,482) Net operating income 1,829 1,712 1,647 1,464 1,652 (1,352) (1,451) (1,488) 1,570 (1,580) +6.1% (5,586) (5,871) +5.1% 1,623 1,600 -1.4% 6,652 6,445 -3.1% Net loan-loss provisions (454) (222) (570) (122) (472) (531) (683) (851) +24.6% (1,368) (2,538) +85.5% Other gains (losses) and provisions (23) 9 (41) (107) (49) (19) (45) (5) -89.0% (162) (118) -27.4% Underlying profit before tax 1,352 1,499 1,036 1,234 1,130 1,021 895 744 -16.9% 5,121 3,790 -26.0% Underlying consolidated profit 1,022 1,139 839 976 877 789 667 588 -11.9% 3,976 2,921 -26.5% Underlying attributable profit 866 956 714 814 867 779 655 576 -12.0% 3,350 2,878 -14.1% Santander 37

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