Charles River - JP Morgan Conference Presentation

Strong and durable industry fundamentals Mid- to high-single- digit growth 10%+ Long-term market growth potential Low-double- digit growth $6.0B Discovery Mid-teens growth 20-25% growth $2.5- Mid-single- $3.0B digit growth $2.5- $3.0B High-single- digit growth $3.0B $5.0- $5.5B Safety Assessment DSA Segment Charles River - JP Morgan Conference Presentation Microbial Solutions Manufacturing Segment RMS RMS $2.0B >$20B Outsourcing continues to increase every year Addressable Market Opportunity Increasingly complex science Note: All growth rates (in green boxes) represent the long-term market sector growth potential. Exposure to high-growth markets 20

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