Investor Presentaiton

NONINTEREST EXPENSE $ in millions Total Noninterest Expense +2% -+4% $1,169 $1,151 $1,118 $1,121 $1,129 $79 $72 $72 $68 $81 $52 $67 $51 $52 $54 $196 $176 $177 $178 $185 ■ $208 $196 $218 $224 $211 $627 $622 $605 $598 $618 4Q 2020 1Q 2021 2Q 2021 3Q 2021 4Q 2021 Compensation & Benefits Outside Services Equipment & Software Occupancy Other Categories may not sum due to rounding. ■ Expenses totaled $1.2 billion in the fourth quarter, up 2% year-over-year and 4% sequentially. The year-over-year growth in expenses was driven by increases in equipment and software related costs, other operating expense, outside services, and employee benefits, partially offset by favorability in occupancy and compensation. The sequential expense performance was driven by increases in compensation and employee benefits, outside services, and equipment and software related costs, partially offset by decreases in occupancy and other operating expense. northerntrust.com | 2022 Northern Trust 7

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