Avantor Results Presentation Deck

Key financial performance metrics ($M, except per share data) Q4 Results Adjusted EBITDA % Adjusted EBITDA Adjusted EBITDA % $320 17.9% Q4'20 YTD Results $1,142 17.9% 2020 +15.6%1 +27.8%1 avantor™ $370 19.4% Q4'21 $1,459 19.8% 2021 Adjusted EPS (Normalized share count)² $0.29 Q4'20 $0.89 2020 +21.4% +57.7% $0.36 Q4'21 $1.41 2021 $286 Q4'20 $868 2020 Free cash flow +9.9% +6.0% $314 Q4'21 $920 2021 1: Includes impact from foreign exchange differences; assuming FX rates of prior corresponding period, foreign exchange translation represented a 1.5% headwind in Q4 and 1.9% tailwind for the year. 2: Assumes shares outstanding of 642.7M for both periods. 8

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