Corporate & Investor Presentation

COPD is a large and growing market + More than 380 million people worldwide are estimated to have COPD1 - - Largely undiagnosed COPD sufferers in high-growth markets such as China, India, Brazil and E. Europe may be well over 100 million 1 $ Cost to healthcare systems from COPD is enormous: + - - · Europe: ~€48 billion per year² United States: -$50 billion per year³ More than 3 million people worldwide die each year due to COPD4 LET'S TALK ABOUT The Long-term Health and Economic Burden of COPD in the United States A recent study publication (Zafari et al. CHEST 2020) modelled the health and economic burden of COPD in the US over 20 years from 2019 to 2038 ${ Direct medical costs attributable to COPD estimated to be $800.90 billion $101.30 billion estimated indirect costs of work absenteeism $337.13 billion $463.77 billion in men in women 315.08 million estimated number of COPD exacerbations 1. Adeloye D et al. J Glob Health 2015 2. ERS White Book. https://www.erswhitebook.org/chapters/the-economic-burden-of-lung-disease/ 3. NHLBI. Morbidity & Mortality: 2009 Chart Book on Cardiovascular, Lung, and Blood Diseases 4. WHO 2017 https://www.who.int/news-room/fact-sheets/detail/chronic-obstructive-pulmonary-disease-(copd) 19 © 2021 ResMed | Corporate & Investor Presentation - updated 28JAN21 9.42 million estimated COPD deaths ResMed

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