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Investor Presentaiton

Hematology Reblozyl BET Inhibitor Breyanzi golcadomide Abecma alnuctamab GPRC5D iber/mezi Pivotal KarMMa-9 in patients with sub-optimal response post-ASCT Inclusion Criteria: Adult patients with PR or VGPR to ASCT Primary Endpoint: PFS Key Secondary Endpoint: • OS Stratification Factors: R-ISS III at initial diagnosis Anti-CD38 induction • VGPR vs PR Ill Bristol Myers Squibb™ NDMM after 4-6 Cycles Induction HDT/ASCT PR or VGPR lenalidomide maintenance 1 cycle R 1:1 Ide-cel manufacturing Apheresis Flu/Cy + ide-cel lenalidomide maintenance (start 1 month after ide-cel/counts recovery; continue until PD) lenalidomide maintenance until PD Pivotal KarMMa-9 study initiating Data anticipated in 2027 Follow-Up Not for Product Promotional Use 84
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