Reshaping the HIV treatment and prevention landscape slide image

Reshaping the HIV treatment and prevention landscape

Improvements in cycle times have been driven by focus, operational excellence gsk and smart risk taking Blenrep (BCMA ADC) - 2H 2018 1H 2019 2H 2019 1H 2020 2H 2020 1H 2021 2H 2021 Approved just over two years after pivotal study start Pivotal study start (Jul) Pivotal data Submission (Aug) (Dec) Approval (Aug) RSV Older Adults - Accelerated development to enable potential first- in-class position sotrovimab (VIR-7831) - Received FDA Emergency Use Authorization 13 months after announcing the deal otilimab (aGM-CSF) - Encouraging Phase 2 data generated for COVID within 8 months of study start Ph1/2 start (Jan) EUA emergency use authorisation Ph1/2 data (May) Ph3 start (Feb) Deal signed (April) Ph1 start (Aug) Ph3 data FDA EUA (Mar) (May) Idea (Mar) Ph2 start (May) Ph2 data Extension (Jan) study (Feb) Extension data (Q3) 49
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