Investor Presentation First Nine Months of 2022

112 Investor presentation First nine months of 2022 GLP-1 market share and market growth 80% 60% 40% 20% 0% GLP-1 market growth and Novo Nordisk market share DKK billion 80% 73% 63% 60% 61% 23 48% 40% 20% 57% 80 GLP-1 market size and growth -48% 3 34 0 Novo NordiskⓇ ~61% 63% 0% Aug 2022 Aug 2021 Novo Nordisk AZ Others Aug 2022 Novo Nordisk Competitors Aug 2019 NN market share -Market growth (Right Axis) NN share of growth NN growth (Right Axis) Source: IQVIA, Aug 2022, Value MAT, all countries; NN: Novo Nordisk

View entire presentation