Q4 2021 Results slide image

Q4 2021 Results

Participants Company overview Pharmaceuticals Oncology Financial review Conclusion Appendix 3 INNOVATION Business development activities adding 4 new mid/late stage high potential medicines GYROSCOPE Acquisition VISION FOR LIFE GT005: One-time subretinal Ph2 gene therapy that could transform care for geographic atrophy, a leading cause of blindness¹ BeiGene Option Ociperlimab: Ph3 TIGIT inhibitor with the potential to treat a wide range of solid tumors; development program includes 6 global trials in lung cancer, ESCC, cervical cancer W Opt-in² MOLECULAR partners Ensovibep: Multi-specific Ph2 DARPinⓇ, specifically designed to block the receptor binding domains of SARS-CoV-2 spike protein ucb Co-development / co-commercialization DLX313 (UCB0599): Potential first-in-class, small molecule, alpha-synuclein misfolding inhibitor in Ph2 Parkinson's Disease DARPin - Designed Ankyrin Repeat Protein. 1. Completion of the transaction is subject to customary closing conditions. Novartis and Gyroscope will continue to operate as separate and independent companies until closing. 2. License Agreement with Molecular Partners signed. 16 Investor Relations | Q4 2021 Results 1 NOVARTIS | Reimagining Medicine
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