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Investor Presentaiton

Strong business momentum Diversified portfolio growth Efficient compounding engine Sustainable long-term growth Long-term growth powered by consistent portfolio replenishment Adjusted Cash Receipts (1) (2) ("top-line") 13% CAGR Unusual period with 4 large royalty expirations: Tecfidera, Remicade, Humira, and Lyrica totaling >$1bn in adjusted cash receipts 11-14% CAGR 10%+ CAGR 2010 2018 2020 2025e Pre-2010 2010-2012 2013-2015 2016-2018 2019-2021 2022-2024 2025-2027 2028-2030 Current portfolio Future royalty acquisitions(3) ROYALTY PHARMA 1. Adjusted Cash Receipts for periods 2020 and earlier are pro forma for current non-controlling interests. See footnote (1) on slide 114 for additional information. 2. See slide 114 for definitions and factors that may impact the achievement of our growth outlook. Growth outlook includes future royalty acquisitions and excludes development-stage pipeline candidate gantenerumab for Alzheimer's disease. Refer to the Appendix for a GAAP to non-GAAP reconciliation. 3. Illustrative analysis calculated using representative cash receipts based on blended average of actual and projected returns for approved and development-stage transactions over the last five years under a range of scenarios. Assumes $2.0-2.5bn of capital deployed on average per year through 2030. 2030e 102
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