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Anemia Intervention Strategies

Review: Oral iron supplements for children in malaria-endemic areas Comparison: Iron versus placebo or no treatment Outcome | Clinical malaria (by anaemia at baseline) Study or subgroup I Angeria log [Risk Ratio] (SE) Risk Ratio MVFixed,95% CI Weight Risk Ratio IMFixed,95% C Adam 1997 (C 0.401106 (0.19702878) 5.9% 1.49 [1.02, 2.20] Ayoya 2009 0.732368 (0.58467408) 0.7% 2.08 [066, 6.54] Desai 2003 -0.52742 (0.19357679) 6.1% 0.59 [040, 0.86] Fahmida 2007 0313161 (0.7553618) 0.4% 1.37 [031, 601] Gebreselassie 1996 0465092 (0.27861906) 2.9% 1.59 [0.92, 2.75] Massaga 2003 -Q1705 (0.14303878) 11.2% 084 [064, 1.12] Massaga 2003 0.054615 (0.23254496) 42% 1.06 [067, 1.67] Smith 1989 (C) 0473541 (0.48487584) 1.0% 1.61 [062, 4.15] Verhoef 2002 0.356675 (031150403) 24% 1.43 [078, 263] Verhoef 2002 0.04256 (0.24648012) 38% 1.04 [064, 1.69] Subtotal (95% CI) 38.5 % 1.02 [0.88, 1.19] Heterogeneity: Chi² = 19.77, df = 9 (P=0.02); 1² =54% Test for overall effect: Z-031 (P = 0.76) 2 No anaemia Harvey 1989 -0.08004 (0.16178459) 8.7% 092 [067, 1.27] Lawless 1994 -0.04652 (0.14975946) 10.2% 095 [071, 1.28] Leenstra 2009 0.625938 (0.7978724) 0.4% 1.87 [0.39,893] Menendez 1997 -0.06236 (0.12627568) 14.3% 094 [073, 1.20] Menendez 1997 -01779 (0.20514197) 5.4% 0.84 [0.56, 1.25] Richard 2006 0044784 (0.10073627) 22.5% 1.05 [0.86, 1.27] Subtotal (95% CI) 61.5 % 0.97 [0.86, 1.09] Heterogeneity: Chi² = 1.92, df = 5 (P=0.86); 1² =0.0% Test for overall effect: Z = 0.48 (P = 0.63) Heterogeneity: Chi² = 21.98, df = 15 (P=0.11); 1²=32% Total (95% CI) Test for overall effect: Z=018 (P = 0.85) Test for subgroup differences: Chi² = 0.29, df = 1 (P=0.59), 1² =0.0% 100.0 % 0.99 [0.90, 1.09] 02 05 2 5
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