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Health Predispositions¹ 30+ Including: Type 2 Diabetes (Powered by 23andMe Research) Coronary Artery Disease 23 andMe+ Uterine Fibroids 23andMe+ Migraine 23 and Me+ MUTYH-Associated Polyposis BRCA1/BRCA2 (selected variants) Type 2 Diabetes YOUR RESULT Your genetics are associated with a typical likelihood. Based on your: XXX Genetics Age 37% 23andMe Personal Genome Service (PGS) The First and Only Multi-Disease DTC Personal Genome Service that Includes FDA-Authorized Reports and Provides Personalized Genetic Insights and Tools 4 Ethnicity Wellness 2 10 Including: Muscle Composition Genetic Weight Alcohol Flush Reaction Saturated Fat and Weight Sleep Movement Dog & Cat Allergies 23andMe+ Genetic Weight YOUR RESULT Your genes predispose you to weigh about 7% less than average. Average 142 lbs Carrier Status 40+ Including: Cystic Fibrosis Sickle Cell Anemia Familial Hyperinsulinism (ABCC8-Related) Tay-Sachs Disease Glycogen Storage Disease (Type 1a) Chromosome Tay-Sachs Disease YOUR RESULT You do not have the variants we tested. 0 variants detected in the HEXA gene 1. Includes FDA Authorized Genetic Health Risk Reports and Wellness Reports for Genetic Likelihood Powered by 23andMe Research. 2. Wellness information does not require FDA Authorization. Pharmacogenetics 3 Including: SLC01B1 Drug Transport CYP2C19 Drug Metabolism .e.g., citalopram and clopidogrel DPYD Drug Metabolism Copyright © 2023 23andMe, Inc. Pharmacogenetics Genetic variants may influence how you process medications. YOUR RESULTS CYP2C19 Drug Metabolism LIKELY NORMAL METABOLIZER DPYD Drug Metabolism LIKELY NORMAL METABOLIZER SLCO1B1 Drug Transport LIKELY NORMAL FUNCTION 8 FDA Authorizations/ Clearances Print summary 23andMe+ 23andMe 20

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