Cytek Investor Day Presentation Deck
HIV: a problem even when virus is undetectable
Despite successful viral suppression via anti-retroviral therapy, HIV+ individuals
have an elevated risk of Serious Non-AIDS (SNA) events:
cardiovascular atherosclerosis Diseases associated with normal aging
neurocognitive degeneration
diabetes mellitus
cancer
osteoporosis
liver (cirrhosis)
frailty
pneumonia
SNAs afflict older HIV+ individuals at higher rates than
the age-matched general population
AIDS Patient Care STDS, 2013. 27(1): p. 5-16.
SNAs occur at younger ages in HIV+ vs uninfected controls
Clin Infect Dis, 2011. 53(11): p. 1120-6.
Do HIV+ individuals age earlier or differently?
Whether HIV causes SNAs through the same mechanism(s) as normal aging or
through other processes is unclear...View entire presentation