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Investor Presentation

GVB: A TRANSFORMATIONAL ACQUISITION The acquisition of GVB allows 22nd Century to leverage its expertise in receptor and plant science to develop its hemp/cannabis franchise and add significant scale in the immediate-term Market Leadership in Hemp-Derived Products Compelling Financial Impact Key Strategic Benefits and Synergies ▪ GVB is wi regarded as a best-in-class operator with an estimated 15% share of the hemp-derived active ingredients market ■ Control from biomass to ingredients to finished goods ensuring attractive prices, quality, purity (99%+ isolates) and traceability ■ CGMP and NSF-audited facility 22ND CENTURY GROUP Significantly increases 22nd Century's revenue and accelerates the path to profitability ■ Immediately accretive to top and bottom line ▪ Manageable working capital investments and limited capital expenditure requirements to drive significant growth ▪ GVB's production and formulation capabilities are uniquely suited to leverage and monetize 22nd Century's IP portfolio and research capabilities ▪ Crop developments by 22nd Century will lead to dramatic margin expansion for GVB sales ▪ Manufacturing capabilities for various form factors represent an under-penetrated growth opportunity that 22nd Century leadership is well-qualified to capitalize on ▪ Deepens global footprint in geographic markets targeted for growth 15
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