Investor Presentaiton

Uptake of allergen by Promising Biologic for Allergic Disease Mast-cell stimulation – Atopic Dermatitis and Asthma Mast cell FCERI Allergen Release of mediators of acute and chronic inflammation mlgE ONENESS dendritic cells IL-4, IL-5 and IL-10 TCR IgE Precursor T helper cell Expansion of TH2-type cells B cell TH2 cell MHC class II TH1 cell Production of IgE Dendritic cell ✓ Anti-IgE Edited from Nature Review | Immunology 2004; IgE: Immunoglobuin E; AD: atopic dermatitis FB825 Anti-Cεmx cytoplasm Plasma membrane 17

View entire presentation