Investor Presentation Q1 2023

22 Investor presentation First three months of 2023 Sales growth of 25%, driven by both NAO and IO with 41% and 10% sales growth respectively Total in DKK billion Historic and reported sales by geography Reported sales and growth breakdown for the first quarter of 2023 Novo NordiskⓇ 111.8 177.0 53.4 Regions Sales (mDKK) Share of Growth growth 9% 14% 13% 10% International Operations 24,070 10% 22% 9% 8% EMEA 12,742 18% 18% 30% 24% 25% Region China 4,461 -5% -2% ROW 6,867 9% 6% North America Operations 29,297 41% 78% 51% 52% 55% Hereof USA 27,322 39% 71% Total sales 53,367 25% 100% 2018 2022 Q1 2023 North America EMEA Region China ROW Source: Quarterly company announcement IO: International Operations; NAO: North American Operations; EMEA: Europe, Middle East, and Africa; RoW: Rest of World; Region China covers mainland China, Hong Kong and Taiwan Note: Numbers may not add up to 100% due to rounding; Growth at Constant exchange rates; Sales numbers are reported in Danish kroner

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