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Investor Presentaiton

SELECT TRIALS - INSULIN EFSITORA ALFA Study Indication* NCT05462756 Type 2 Diabetes NCT05275400 Type 2 Diabetes NCT05662332 Type 2 Diabetes NCT05463744 Type 1 Diabetes Title A Study of Insulin Efsitora Alfa (LY3209590) as a Weekly Basal Insulin Compared to Insulin Glargine in Adult Participants With Type 2 Diabetes on Multiple Daily Injections (QWINT-4) A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 2 Diabetes Currently Treated With Basal Insulin (QWINT-3) A Study of Insulin Efsitora Alfa (LY3209590) Compared to Glargine in Adult Participants With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time (QWINT-1) A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy (QWINT-5) A Study of Insulin Efsitora Alfa (LY3209590) Compared to NCT05362058 Diabetes Degludec in Adults With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time (QWINT-2) * Molecule may have multiple indications ** Trial may have additional primary and other secondary outcomes Not for promotional use Phase Patients Primary Outcome* ** Lilly Primary Completion Completion 3 730 Change from Baseline in Hemoglobin A1c (HbA1c) Mar 2024 Mar 2024 3 986 Change from Baseline in Hemoglobin A1c (HbA1c) May 2024 May 2024 3 796 Change from Baseline in Hemoglobin A1c (HbA1c) Jul 2024 Jul 2024 3 692 Change from Baseline in Hemoglobin A1c (HbA1c) May 2024 May 2024 3 912 Change from Baseline in Hemoglobin A1c (HbA1c) Apr 2024 Apr 2024 Source: clinicaltrials.gov, July 13, 2023 2023 Q2 EARNINGS 37
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