Investor Presentation - First Six Months of 2021

112 Investor presentation First six months of 2021 Diabetes market share and market growth in North America Operations. Diabetes market growth and Novo Nordisk market share 50% DKK Diabetes market size and growth -5% billion 10 01 6 8 463 40% 30% 20% 34% 32% ~5% NAO 487 10% 5% 32% 32% 5% 0% May -NN market share NN share of growth May May Novo Nordisk BI Others May 2018 2021 2020 2021 -Market growth NN growth Novo Nordisk Competitors Source: IQVIA, May 2021, value, MAT; NN: Novo Nordisk

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