Investor Presentation Full Year 2021

119 Investor presentation Full year 2021 GLP-1 market share and market growth in North America Operations GLP-1 market growth and Novo Nordisk market share 60% 40% 20% GLP-1 market size and growth -31% 18 DKK billion 58% 22 52% 124 36% 31% 50% ~36% NAO 163 -2 52% 0% Nov 2018 NN market share NN share of growth Nov Nov Novo Nordisk Eli Lilly Others Nov 2020 2021 2021 Market growth -NN growth Novo Nordisk Competitors Source: IQVIA, Nov 2021, value, MAT; NN: Novo Nordisk

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