Guardant Health Investor Presentation

Medicare and strong private payer coverage today and opportunity for increased coverage post FDA approval Q2 2016 Q3 2017 Q4 2017 Q1 2018 Q3 2018 Q4 2018 Priority Health CareFirst Cigna MASSACHUSETTS South Carolina HUMAN SERVICES USA UPMC Medicare BlueCross BlueShield Association FLORIDA Horizon blue california ® Total Covered Lives (Estimated) 700K 3.7M 6.9M 21.9M 89.9M Estimates for Q2 2016 through Q4 2019 are as of 1/04/2019 115.3M 14 GUARDANT™

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