Fourth Quarter & Full Year 2022 Financial & Business Update slide image

Fourth Quarter & Full Year 2022 Financial & Business Update

Expenses Reflect Investment in Pipeline and Commercial Expansion In millions 4Q21 3Q22 4Q22 FY21 FY22 Cost of sales $87 $108 $108 $312 $410 Cost of sales increase reflects higher product sales and profit share and includes royalties as well as non-cash amortization R&D expenses $304 $385 $358 $1,229 $1,344 SG&A expenses $211 $210 $216 $716 $821 Total costs & expenses $602 $703 $682 $2,256 $2,575 Other income (loss) 1 ($3) $2 $6 $8 $3 Net income (loss) $175 ($191) ($148) ($674) ($610) • R&D expenses reflect continued investment to expand the potential of our approved products and to advance our pipeline programs SG&A expenses driven by ongoing commercialization efforts and other corporate activities to support our growing business Seagen 1 Includes Investment and other income (loss) and income taxes; Amounts may not total due to rounding 19
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