J.P. Morgan Healthcare Conference Presentation slide image

J.P. Morgan Healthcare Conference Presentation

Investor roadmap highlights progress of key events Execution Pipeline Phase III and regulatory decisions² Q2 2023 Q2 and Half-year 2023 results Full-year 2023 upgraded guidance ✓ Therapy Area Strategy R&D priorities Arexvy US > > regulatory approval ☑ Arexvy second season data BELLUS Health, Inc. acquisition completed SCYNEXIS, Inc. exclusive license completed K Q3 2023 Q3 and Year-to-date 2023 results Arexvy RSV, ≥60 YOA (JP) Arexvy, RSV, 50-59 YoA Q4 2023 Full-year and Q4 2023 results Performance vs BIU 20211 Full-year 2024 guidance Apretude, HIV pre-exposure (EU) Vocabria, HIV treatment (CN) Ojjaara, MOMENTUM, myelofibrosis (US) Jemperli RUBY, 1L DMMR/MSI-H EC³ (US) >> > > > > H1 2024 Q1 2024 results Q2 and Half-year 2024 results Jemperli: RUBY, IL dMMR/MSI-H EC³ (EU) ☑ • Ojjaara: MOMENTUM, myelofibrosis (EU, JP) • Blenrep: DREAMM-7, 2L+ MM ✓ • gepotidacin: EAGLE-1, GC ° depemokimab: SWIFT-1/2, asthma • Jemperli: RUBY (Part 2), 1L EC³ ☑ • Jemperli: RUBY (Part 1) 1L OS4 EC3 ° Zejula: FIRST, IL maintenance OC ovarian cancer Capital Allocation Capital allocation R&D and BD priorities TA priorities く > > Full-year 2023 dividend declaration Roadshows Investor Engagement Meet the management, Meet the management, HIV Infectious Diseases Meet the management, Respiratory Meet the management, Oncology Medical congresses GSK 1. June 2021 Investor Update 2. Includes phase III data readouts and regulatory decisions with the applicable geography denoted in brackets 3. Endometrial cancer 5. cholestatic pruritus in primary biliary cholangitis • • H2 2024 Q3 and Year-to-date 2024 results Full-year and Q4 2024 results Performance vs BIU 20211 Guidance 2025 Arexvy: RSV, 50-59 YOA (US, EU, JP) Nucala: CRSwNP (JP) Nucala: severe asthma (CN) depemokimab: ANCHOR-1/2, CRSWNP Nucala MATINEE, COPD cobolimab: COSTAR, 2L NSCLC Blenrep: DREAMM-8, 2L MM Zejula: ZEAL, IL maintenance NSCLC linerixibat: GLISTEN, PBC5 Full-year 2024 dividend declaration 4. Overall survival population 11
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