Investor Presentaiton

Prognos-Company Overview Market Segment: Headquarters: CEO: COMPANY OVERVIEW Healthcare Analytics / Al New York, NY Sundeep Bhan Prognos aggregates, harmonizes and analyzes clinical diagnostic data for life sciences, diagnostic companies, and payers, aiming to improve health by tracking and predicting disease • The Prognos Registry of 22 billion clinical records for 200 million patients in over 50 disease areas enables earlier identification of patients who can benefit from enhanced treatment decision making and risk management • The Company operates in two verticals - Life Sciences and Payers. In the Life Sciences segment. Prognos contracts with biopharma firms to identify patients who are candidates for drug treatment. ⚫ In the Payer segment, Prognos contracts with plans for various population risk use cases annually and has revenue share agreements with labs to secure access to the data Origin: Capital: Ownership: Financing Rounds: Other Investors: prognos SUMMARY November 2011 $12.6M 29% Primary / 25% Fully Diluted Series A, Series B, Series C Hikma Ventures, Cigna Ventures, ARC Angel Fund, Merck GHIF, GIS Strategic Ventures (Guardian Life), Hermed Capital, Maywic Strategic Inv Board Member: Gary Kurtzman (Chair) REVENUE MODEL THESIS Large, unique clinical data asset; proprietary technology and data science/machine learning/Al capabilities; data network effects Multiple use cases applicable to pharma, payers, labs, and PBMs with potential for expansion into provider space • Based on current monetization strategies, the total addressable healthcare analytics market for Prognos' products is estimated to reach $5.5bn+ Strategic partnership opportunities Prognos operates in two verticals - Life Sciences and Payers. In the Life Sciences segment, Prognos contracts with biopharma firms for potential patient identification solutions. In the Payer segment, Prognos contracts with plans for various population risk use cases annually and has revenue share agreements with labs to secure access to the data. COMPETITORS IQVIA, Health Verity, LabCorp, Quest, Symphony Health, Komodo Health G www.safeguard.com © 2021 Safeguard Scientifics, Inc. All rights reserved. SFE LISTED NYSE 22 222

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