Investor Presentaiton
Clarity's proprietary SAR Technology platform
Theranostic radiopharmaceuticals have four main elements: a radioisotope, cage, linker and targeting ligand
and are administered intravenously
Tumour
Tumour specific
receptors
Proteins expressed by
cancer cells which the
radiopharmaceuticals target
Radioisotope
Copper isotopes used, for example, in
Positron Emission Tomography (PET)
imaging (64Cu) or therapy (67Cu)
Targeting molecule
Finds and binds cancer
cells in the body
Linker
Cage
"Chelator" that
securely holds
radioisotopes
That connects the cage to
the targeting molecule
Ⓒ CLARITY
PHARMACEUTICALS
SAR Technology
platform
A proprietary, highly
specific and highly
stable bifunctional cage
(chelator) with a
superior ability to retain
copper isotopes within
it and prevent their
leakage into the body
Unlike the current
I generation of
|
radiopharmaceuticals,
SAR products do not
I require heating in
I order to bind copper
I
to the cage
CLARITY
2014 MEIE
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