Investor Presentation Full Year 2021

116 Investor presentation Full year 2021 Diabetes market share and market growth in North America Operations NAO Diabetes market growth and Novo Nordisk market share Diabetes market size and growth 50% DKK ~10% billion 15 525 15 17 477 40% 30% 20% 10% 36% 32% 11% 10% 32% ~11% 32% 0% Nov -NN market share NN share of growth Nov Nov Novo Nordisk Lilly Others Nov 2018 2021 2020 2021 -Market growth NN growth Novo Nordisk Competitors Source: IQVIA, Nov 2021, value, MAT; NN: Novo Nordisk

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