Reimagining Medicine Q2 2023 Results slide image

Reimagining Medicine Q2 2023 Results

Company overview Financial review Conclusions Appendix References EntrestoⓇ delivering strong double-digit growth in all geographies Sales evolution USD m, % cc US weekly TRX1 Total prescriptions (000) 110 Ex-US US 100 +37% 90 1,516 80 200 70 1,125 761 60 50 577 40 30 755 20 548 210 10 0 Q2 2022 Q2 2023 July 2015 June 2023 GROWTH Entresto® Strong Q2 momentum US: sales +38% cc, NBRx +17% vs PY, ~1.3m TRx in Q21 Ex-US: sales +36% cc, continued strong growth in HFrEF China/Japan: Significant contribution from HTN² Confidence in future growth Robust guidelines³ (US/EU) Expect further penetration in HFrEF (2/3 eligible patients still on prior SoC) PARAGLIDE in HFPEF met primary endpoint5 Pediatric approval confirms RDP to Nov 2026 EU4 US IP update Mylan held to infringe crystalline complex patents; Novartis disagrees with negative decision by Delaware Court and will appeal to uphold validity of combination patent TRX total prescriptions. See last page for references. Constant currencies (cc), core results are non-IFRS measures; explanation can be found on page 48 of Condensed Interim Financial Report. HFPEF-heart failure with preserved ejection fraction. HFrEF-heart failure with reduced ejection fraction. HF heart failure. HTN hypertension. RDP Regulatory data protection. SOC 6 Investor Relations | Q2 2023 Results NBRX-new to brand prescriptions. standard of care. ✓ NOVARTIS | Reimagining Medicine
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