Investor Presentation Full Year 2021

107 Investor presentation Full year 2021 Diabetes market share and market growth in Rest of World 20% 15% 10% 5% 0% -5% Diabetes market growth and Novo Nordisk market share -10% Nov 2018 NN market share NN growth (right axis) Diabetes market size and growth ~4% Rest of World 25% DKK million 16% 20% 2 1 62 60 20% -1 15% 10% 4% 5% 0% ~20% 14% 16% -5% Nov Nov Novo Nordisk BI Others Nov 2021 2020 2021 Novo Nordisk Competitors -Market growth (right axis) Source: IQVIA, Nov 2021, value, MAT, Rest of world; NN: Novo Nordisk BI: Boehringer Ingelheim

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