Investor Presentation Full Year 2021

105 Investor presentation Full year 2021 GLP-1 market share and market growth in Region China Region China 120% 80% 40% 0% Nov GLP-1 market growth and Novo Nordisk market share 2018 NN market share NN Share of Growth -Market growth (right axis) Source: IQVIA, Nov 2021, Value, MAT; NN: Novo Nordisk GLP-1 market size and growth 160% DKK million 120% 105% 74% 80% 694 68% 40% 90% ~105% 233 70 1,426 429 ~68% 74% 0% Nov Nov Novo Nordisk Eli Lilly Others Nov 2021 2020 2021 Novo Nordisk Competitors

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