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Immunology Investor Event

Sanofi ambition to address unmet medical needs for a broad spectrum of AD and Asthma patients Mild Moderate-Severe sanofi AD sanofi Asthma Inhalers disease control, but Topicals safe and efficacious noncompliance an issue Safe Orals for less severe AD Topical BTKI rilzabrutinib IRAK-4 degrader rilzabrutinib Others AD and Asthma Except with respect to Dupixent, all listed agents are investigational and the safety and efficacy has not been evaluated by any regulatory authority 29 Immunology Investor Event sanofi Potential for higher efficacy biologics Injectables novel MoAs DUPIXENT (dupilumab) amlitelimab (T2 and mixed) anti-IL-13/OX40L NanobodyⓇ VHH DUPIXENT (dupilumab) amlitelimab (T2 and non-T2) anti-IL-13/TSLP NanobodyⓇ VHH anti-IL-13/OX40L NanobodyⓇ VHH Marketed injectables
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