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Investor Presentaiton

PBF It takes Protection Beyond Flu to win Fluzone HD share of U.S. 65+ years old flu market value, $bn Immunogenicity Superior Efficacy Fluzone HD and Flublok in CDC preferential recommendation for 65+ Protection Beyond Flu 1.7 1.6 1.4 1.0 1.1 0.8 0.7 0.6 0.4 0.5 0.3 0.3 0.3 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 Other Fluzone HD Source: Sanofi internal analysis 43 Vaccines Investor Event sanofi

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