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Investor Presentaiton

20 How to INVEST in São Paulo STATES 21 BENCHMARK IN RESEARCH AND DEVELOPMENT Many different companies, organizations and institutions in the field of research and development are located in São Paulo State. Below are some of them. Adolfo Lutz Institute The Adolfo Lutz Institute is internationally recognized for its competence to respond to instances in its areas of expertise: bromatology and chemistry, medical biology and pathology. The institute has been accredited by the Ministry of Health as National Public Health Laboratory and Macro-regional Benchmark Laboratory. It is a collaborating center of the joint program to monitor contaminants in food developed by the United Nations Food and Agriculture Organization (FAO) and the World Health Organization (WHO). The Institute is also a benchmark for analytical quality control of mycotoxins and pesticide residues; national coordinator of the monitoring program of extraneous substances in food; national benchmark center for laboratory diagnosis of HIV; collaborating center of the Pan American Health Organization (PAHO) in the areas of arboviruses, influenza virus and manufacture of immunobiological products and PAHO collaborating center for cell cultures. To learn more, please visit their website at www.ial.sp.gov.br Biological Institute The Biological Institute offers significant solutions to agribusiness and transfers them to the productive sector. With activities in the fields of animal and plant health and in their relations with the environment, the institute contributes to development, production costs reduction, social inclusion and environmental protection, promoting population welfare. To learn more, please visit their website at www.biologico.sp.gov.br Butantan Institute The Butantan Institute, linked to São Paulo State's Secretariat of Health, is one of the largest biomedical research centers in the world, accounting for more than 93% of immune serums and vaccines produced in Brazil, among which vaccines against diphtheria, tetanus, pertussis, hepatitis B, seasonal influenza and HINI. The Institute develops the following activities: * Basic research and studies in Biology and Biomedicine, directly or indirectly related to public health; Scientific missions in Brazil and abroad through the WHO and PAHO, UNICEF and the UN; • Cooperation with agencies of the Ministry of Health and of the State Secretariat of Health, National Institute of Health (U.S.) and the Bill & Melinda Foundation (Bill Gates foundation dedicated to research and community action in health) in fighting epidemic outbreaks. Butantan has a beautiful park with 80 hectares and more than 62% of green area, attracting over 300 thousand visitors annually. It is one of the main tourist attractions of the city of São Paulo. To learn more, please visit their website at www.butantan.gov.br Campinas Institute of Agronomy (IAC) The Campinas Institute of Agronomy (IAC) is the research branch of the São Paulo Agency for Agribusiness Technology, a subsidiary of the Secretary of Agriculture and Food Supply of the State of São Paulo. Founded in 1887, the institution's mission is to create and transfer science and technology to the agriculture sector, with the goal of improving systems from planting all the way to socio-economic development with environmental quality. The IAC's activities guarantee the availability of food to the population and of raw materials to industry, cooperating to assure both food supplies and the competitiveness of products in both the domestic and export markets. To learn more, please visit their website at www.iac.sp.gov.br Dante Pazzanese Institute of Cardiology The Dante Pazzanese Institute of Cardiology is a leading cardiac care center in Brazil, linked to the São Paulo State Secretariat of Health. Its mission is to provide, with excellence, humanized healthcare to patients with cardiovascular diseases, promoting education and research. To learn more, please visit their website at www.dantepazzanese.org.br Forestry Institute The Forestry Institute is a pioneering entity in terms of actions of nature conservation, holding a strong position in São Paulo's and Brazilian's forestry field, acting as a generator of sustainable economic activity, and in the protection of significant areas of primitive ecosystems. The institute is a standout regarding forestry research for genetic improvement for increasing productivity in the production of pinus resin. This is an essential contribution to the sector, considering Brazil is currently the second largest resin producer in the world, behind China. In addition, the institute is a major producer of forest seeds and seedlings of native and exotic species for different purposes. To learn more, please visit their website at www.iflorestal.sp.gov.br
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