Q3 2023 Results - Reimagining Medicine slide image

Q3 2023 Results - Reimagining Medicine

Company overview Financial review Conclusions Appendix References EntrestoⓇ delivers 31% growth with sales approaching USD 1.5bn in the quarter Sales evolution USD m, % cc GROWTH Entresto US weekly TRX1 Total prescriptions (000) 110 826 Strong Q3 momentum ■ US: robust growth outpacing market, sales +28% cc, ~1.4m TRx in Q31 ■ Ex-US: sales +34% cC ◉ China/Japan: significant contribution from HTN² Confidence in future growth Ex-US US 100 +31% 90 1,485 80 70 1,135 757 60 50 565 40 30 728 570 220 10 0 Q3 2022 Q3 2023 July 2015 See last page for references. RDP Regulatory data protection. Sept 2023 ■ Strong guidelines position³ (US/EU) ■ Expect further penetration in HF (2/3 eligible patients still on prior SoC) and HTN (China/Japan) ■ EU: paediatric approval confirms RDP to Nov 20264 ■ US: appeal filed to uphold validity of combination patent; other patent litigation ongoing and no generics have FDA approval 5 Constant currencies (cc), core results are non-IFRS measures; explanation can be found on page 48 of Condensed Interim Financial Report. SOC standard of care. TRX total prescriptions. HF heart failure. HTN hypertension. 6 Investor Relations | Q3 2023 Results ✓ NOVARTIS | Reimagining Medicine
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