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Investor Presentaiton

Aggregate Portfolio Revenue TTM through 3/31/2021 Revenue (in millions) $400 $350 $300 $107 $37 $53 $250 $19 $193 $200 $150 $262 $252 $232 $248 $100 $127 $50 $- 3/31/2017 3/31/2018 3/31/2019 Actual Actual Actual 3/31/2020 Actual 3/31/2021 Actual ■Digital Marketing and other Healthcare Aggregate annual revenue rate down 9.7% Average annual revenue growth rate of 14.1% Aggregate annual revenue growth for healthcare portfolio of 3.5% Note: trailing twelve-month revenues as of 3/31/2021, reflects one quarter reporting lag; includes Flashtalking and excludes Bright Health Group. G www.safeguard.com SFE © 2021 Safeguard Scientifics, Inc. All rights reserved. LISTED NYSE Healthcare Companies (7) Digital Media and other companies (4) Note: SFE reports the revenue of its companies on a one-quarter lag basis. Revenue for all years has been revised to exclude companies that were exited or fully impaired. Certain amounts in 2018 and 2019 have also been adjusted to reflect the impact of revenue accounting changes adopted at applicable companies. 50
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