2023 Guidance and Q3 Earnings slide image

2023 Guidance and Q3 Earnings

Vaccines: +34% with strong Arexvy launch contributing £709m AREXVÝ* (RESPIRATORY SYNCYTIAL VIRUS VACCINE, ADJUVANTED) 83m adults age 60+ in US; 400m globally Launches underway in US, Europe and Canada; approval in Japan >60% US retail market share ~50% of doses co-administered with flu vaccines Available in all major US retail pharmacies 94.6% efficacy in comorbid population resonating well with 66% of HCPs², recalling Arexvy by name³ ~1.4 million US adults vaccinated during Q3 TRX (m) 1.4 Arexvy US TRX since launch 1.2 1 0.8 0.6 0.4 0.2 0 31 32 33 34 35 36 37 38 39 Week number Arexvy Competitor GSK Absolute values at AER; changes at CER, unless stated otherwise 1. Excluding COVID-19 solutions 2. Healthcare Professionals 3. US HCP RSV ATU: Jun 22 (n=260), Jun 23 (n=147), Jul 23 (n=145), Aug 23 (n=149) 15
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