Certara Investor Day Presentation Deck
Addressing safety issues consistently and earlier
Secondary Intelligence
CERTARA ToxStudio®: Secondary Intelligence™ (V1.0)
Projects Project Compounds Receptors Compound Assessment Thresholds
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Compound assessment for Compound A
Compound Assessment Compound Comparison
Focus Compound
Receptor
B2-adrenoceptor
ENT 1 adenosine
ACHE
PDE 40
B1-adrenoceptor
PDE 3A
C1A-adrenoceptor
2A-adrenoceptor
H 2 histamine
SERT serotonin
Compound A
Compound B
Compound C
Compound D
Compound E
Compound F
Compound G
v1
Compound H
Compound I
Compound J
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Toxicology and safety pharmacology
impact organ-specific drug exposure
Biosimulation tools can simulate and
predict safety issues
More efficient and consistent than
traditional method
Reduction in animal use
Relevant for adjacent industries
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