BioAtla Investor Presentation Deck
CAB-AXL (BA3011) Phase 2, part 1 Topline Interim Analysis Results in Sarcoma
Following BA3011 in remaining sarcoma subtypes
Sarcoma Subtype
# of Pt
Leiomyosarcoma
Synovial
Liposarcoma
Osteosarcoma
Ewing sarcoma
Bone Other: (Chondro/Chordo)
Combo CD20 Positive
Combo CD20 Negative
bicatla
19
13
7
8
12
8
8/3
14
12
PFS rate
28.8% (Q2W)
10.3% (3Q4W)¹
35.7%
62.5%
45.5%
18.8%
62.5%/66.7%
32.1%
41.7%
¹Low patient compliance
PFS, progression-free survival; PR, partial response; UPS, undifferentiated pleomorphic sarcoma; NE, not evaluable
Confidential
Partial Response/
Complete Response
0
0
0
2 PRs
0
0
1 PR (UPS)
1 PR (LMS)
'Go' if ≥1 CR/PR
or PFS rate at 3
months >40%;
'No Go' if 0 CR/PR
and PFS rate at 3
months <40%;
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